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LRP5 Rabbit pAb

This product is only available in the US
CNA0130P
Antibody
100 µl

$450.00

DATA SHEET

TargetLRP5 
Product TypeAntibody
ApplicationICC, IF, WB
Conjugateunconjugated
IsotypeIgG
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 1400-1500 of human LRP5 (NP_002326.2).
Host SpeciesRabbit
Species ReactivityMouse, Rat
FormulationPBS with 0.05% proclin300,50% glycerol
Research AreaCancer, Immunology, Metabolism
Description/Background

This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This Protein A Affinity purificationlso acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy. Alternative splicing results in multiple transcript variants.

ProtocolsICC, IF, WB
Components179kDa
Molecular Weight179kDa
PurityAffinity purification
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
This product is only available in the US
CNA0130P
Antibody
100 µl

$450.00

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