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MET Rabbit pAb

This product is only available in the US
CNA0040T
Antibody
100 µl

$450.00

DATA SHEET

TargetMet
Product TypeAntibody
ApplicationWB
Conjugateunconjugated
IsotypeIgG
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 518-840 of MET (NP_000236.2).
Host SpeciesRabbit
Species ReactivityRat
FormulationPBS with 0.01% thimerosal,50% glycerol
Research AreaCancer, Immunology, Epigenetics
Description/Background

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers.

ProtocolsWB
Components156kDa
Molecular Weight156kDa
PurityAffinity purification
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
This product is only available in the US
CNA0040T
Antibody
100 µl

$450.00

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