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STAT1 Rabbit pAb

This product is only available in the US
CNA0027T
Antibody
100 µl

$450.00

DATA SHEET

TargetSTAT1
Product TypeAntibody
ApplicationIHC (P), WB
Conjugateunconjugated
IsotypeIgG
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 650-750 of human STAT1 (NP_009330.1).
Host SpeciesRabbit
Species ReactivityHuman, Mouse
FormulationPBS with 0.01% thimerosal,50% glycerol
Research AreaCancer, Immunology, Epigenetics
Description/Background

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. The protein encoded by this gene can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. The protein plays an important role in immune responses to viral, fungal and mycobacterial pathogens. Mutations in this gene are associated with Immunodeficiency 31B, 31A, and 31C.

ProtocolsIHC (P), WB
Components87kDa
Molecular Weight87kDa
PurityAffinity purification
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
This product is only available in the US
CNA0027T
Antibody
100 µl

$450.00

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