Anti-Integrin αvβ6 ELISA Kit (US only)
This product is only available in the US
5288
ELISA Kit
96 Wells
$2,880.00
Anti-Integrin αvβ6 ELISA Kit is intended to be used for quantitative measurement of anti-integrin αvβ6 antibody in human serum samples.
| Target | Integrin alpha-V / Beta-6 |
|---|---|
| Product Type | ELISA Kit |
| Application | ELISA |
| Research Area | Cell Biology |
| Description/Background | Integrins are heterodimeric cell surface receptors involved in cell-extracellular matrix and cell-cell adhesion. In addition, integrins convey two-way signaling between cells and their surroundings and participate in the regulation of variety of cellular processes. This includes cell proliferation, migration, survival, tissue invasion, and innate immunity. Mammalian cells have 18 distinct integrin alpha subunits and 8 beta subunits, which can combine in various ways to form 24 different receptor heterodimers. Integrin αvβ6 is expressed exclusively by epithelial cells and functions as a receptor for extracellular matrix proteins such as fibronectin. |
| Storage Temperature | Upon receipt, store all components at 2-8°C |
| Protocols | ELISA |
| Sensitivity | 0.4 U/mL |
| Publications | 1. Koivisto L, Bi J, Häkkinen L, Larjava H. Integrin αvβ6: Structure, function and role in health and disease. Int J Biochem Cell Biol. 2018;99:186-96. 2. Kuwada T, Shiokawa M, Kodama Y, Ota S, Kakiuchi N, Nannya Y, et al. Identification of an Anti-Integrin αvβ6 Autoantibody in Patients With Ulcerative Colitis. Gastroenterology. 2021;160(7):2383-94.e21. |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |
This product is only available in the US
5288
ELISA Kit
96 Wells
$2,880.00
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