PIAS1 Rabbit pAb
| Target | PIAS1 |
|---|---|
| Product Type | Antibody |
| Application | WB |
| Clonality | Polyclonal |
| Conjugate | unconjugated |
| Isotype | IgG |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-140 of human PIAS1 (NP_057250.1). |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse, Rat |
| Formulation | PBS with 0.09% Sodium azide,50% glycerol |
| Research Area | Cancer, Epigenetics |
| Description/Background | This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. This protein plays a central role as a transcriptional coregulator of numerous cellular pathways includign the STAT1 and nuclear factor kappaB pathways. Alternate splicing results in multiple transcript variants. |
| Storage Temperature | Store at -20℃ |
| Protocols | WB |
| Molecular Weight | 72kDa |
| Purification | Affinity purification |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |