Neurofilament H Rabbit pAb
| Target | Neurofilament H |
|---|---|
| Product Type | Antibody |
| Application | IF/ICC, IP, WB |
| Clonality | Polyclonal |
| Conjugate | unconjugated |
| Isotype | IgG |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 873-1020 of human Neurofilament H (NP_066554.2). |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse, Rat |
| Formulation | PBS with 0.09% Sodium azide,50% glycerol |
| Research Area | Cancer |
| Description/Background | Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. |
| Storage Temperature | Store at -20℃ |
| Protocols | IF/ICC, IP, WB |
| Molecular Weight | 112kDa |
| Purification | Affinity purification |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |