Target | DNMT3B |
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Product Type | Antibody |
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Application | IF/ICC, WB |
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Clonality | Polyclonal |
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Conjugate | unconjugated |
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Isotype | IgG |
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Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 345-475 of human DNMT3B (Q9UBC3). |
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Host Species | Rabbit |
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Species Reactivity | Human, Mouse, Rat |
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Formulation | PBS with 0.09% Sodium azide,50% glycerol |
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Research Area | CancerEpigenetics |
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Description/Background | This protien enables methylcytosine dioxygenase activity. Involved in several processes, including dendrite morphogenesis; inner cell mass cell differentiation; and protein O-linked glycosylation. Acts upstream of or within DNA demethylation; regulation of DNA methylation; and regulation of genetic imprinting. Located in nucleus. Is expressed in several structures, including brain; early conceptus; embryo ectoderm; lower urogenital tract; and reproductive system. Orthologous to human TET1 (tet methylcytosine dioxygenase 1). |
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Storage Temperature | Store at -20℃ |
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Protocols | IF/ICC, WB |
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Molecular Weight | 96kDa |
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Purification | Affinity purification |
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Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |
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