| Target | DiMethyl-Histone H4-K20 |
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| Product Type | Antibody |
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| Application | ChIP, ChIP-seq, IF/ICC, IHC (P), IP, WB |
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| Clonality | Polyclonal |
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| Conjugate | unconjugated |
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| Isotype | IgG |
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| Immunogen | A synthetic dimethylated peptide around K20 of human histone H4 (NP_003529.1). |
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| Host Species | Rabbit |
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| Species Reactivity | Human, Mouse, Other (Wide Range), Rat |
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| Formulation | PBS with 0.09% Sodium azide,50% glycerol |
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| Research Area | CancerEpigenetics |
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| Description/Background | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy. |
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| Storage Temperature | Store at -20℃ |
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| Protocols | ChIP, ChIP-seq, IF/ICC, IHC (P), IP, WB |
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| Molecular Weight | 11kDa |
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| Purification | Affinity purification |
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| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |
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