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Phospho-RIPK1/RIP-S166 Rabbit pAb

CNAP1230T
Antibody
100 µl

THIS ITEM HAS BEEN DISCONTINUED

DATA SHEET

TargetRIPK1
Product TypeAntibody
ApplicationWB
IsotypeIgG
ImmunogenA synthetic phosphorylated peptide around S166 of human RIPK1/RIP (NP_003795.2).
Host SpeciesRabbit
Species ReactivityHuman, Mouse
FormulationPBS with 0.01% thimerosal,50% glycerol
Research AreaCancer, Immunology
Description/Background

The protein encoded by this gene is a DNA binding cytosolic protein that catalyzes the synthesis of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) after sensing the presence of DNA in the cytoplasm. cGAMP binds another protein, Stimulator of interferon genes (STING), leading to the induction of interferons, and a host immune response. Reduced expression of this gene inhibits interferon induction in the presence of some viral infections. Alternative splicing results in multiple transcript variants.

ProtocolsWB
Molecular Weight76kDa
PurityAffinity purification
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
CNAP1230T
Antibody
100 µl

THIS ITEM HAS BEEN DISCONTINUED
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