[KD Validated] Proprotein Convertase 9(PCSK9) Rabbit mAb

Name: [KD Validated] Proprotein Convertase 9(PCSK9) Rabbit mAb
SKU: CNA11532P
Price: 500.00 USD
Availability: InStock

Code CNA11532P

Product Type Antibody

Size 100 µl

THIS ITEM HAS BEEN DISCONTINUED

Target	PCSK9
Product Type	Antibody
Application	WB
Clonality	Monoclonal
Conjugate	unconjugated
Isotype	IgG
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 593-692 of human Proprotein Convertase 9(PCSK9) (NP_777596.2).
Host Species	Rabbit
Species Reactivity	Human
Formulation	PBS with 0.05% proclin300,0.05% BSA,50% glycerol
Research Area	Cancer, Immunology, Metabolism
Description/Background	<p>This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process Protein A Affinity purificationnd peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia. Alternative splicing results in multiple transcript variants.</p>
Protocols	WB
Molecular Weight	74kDa
Concentration	1 mg/mL
Purity	Affinity purification
Regulatory Statement	For Research Use Only. Not for use in diagnostic procedures.