HSP60/HSPD1 Rabbit mAb
| Target | HSPD1 |
|---|---|
| Product Type | Antibody |
| Application | ICC, IF, IHC (P), WB |
| Clonality | Monoclonal |
| Conjugate | unconjugated |
| Isotype | IgG |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 350-450 of human HSP60/HSPD1 (P10809). |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse, Rat |
| Formulation | PBS with 0.02% sodium azide,0.05% BSA,50% glycerol |
| Research Area | Cancer, Immunology, Metabolism |
| Description/Background | This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13. |
| Protocols | ICC, IF, IHC (P), WB |
| Molecular Weight | 61kDa |
| Purity | Affinity purification |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |