Tetramer/BV421 – HLA-A*02:01 WT-1 (RMFPNAPYL)
The α3 mutation significantly reduces the binding of MHC tetramer to human CD8. To minimizes the aberrant effect of some CD8 antibodies; clone SFCI21Thy2D3 (also known as “T8”) is recommended.
| Target | Cancer |
|---|---|
| Product Type | Tetramer |
| Application | FCM |
| Conjugate | BV421 |
| Class | Class I |
| Species Reactivity | Human |
| Allele | HLA-A*02:01 |
| Peptide Sequence | RMFPNAPYL |
| Research Area | Immunology, Immune Monitoring |
| Protocols | FCM |
| Specificity | WT1 |
| Storage Temperature | 4°C |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |
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