| Target | CD81 (TAPA1) |
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| Product Type | Antibody |
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| Application | FCM, ELISA, exosome isolation, WB |
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| Clonality | Monoclonal |
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| Conjugate | Biotin |
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| Isotype | IgG2a ĸ |
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| Immunogen | Human prostate carcinoma cell line (PC3) derived exosomes (prepared by ultracentrifugation from cultured supernatant) |
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| Host Species | Mouse |
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| Species Reactivity | Human |
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| Formulation | 1 mg/mL in PBS/1% BSA/0.1% ProClin 950 |
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| Research Area | Cancer, Immunology, Epigenetics, Exosomes |
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| Description/Background | CD81 antigen, also known as TAPA1, is a tetraspanin characterized by four transmembrane domains and a member of the transmembrane 4 superfamily. CD81 has broad tissue distribution and may play multiple roles in a variety of cellular processes such as immune response and tumorigenesis, but its function has not been elucidated entirely. It is reported that the tetraspanins CD9, CD63 and CD81 are highly enriched on a certain type of extracellular vesicles, called exosome. Because of various exosome features, CD81, one of the representative exosome surface proteins, is thought to be related to cell-cell communication. |
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| Storage Temperature | 4°C |
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| Protocols | FCM, ELISA, exosome isolation, WB |
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| Clone Number | A103-10 |
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| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |
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