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Anti-BID (Human) mAb (Monoclonal Antibody)

M072-3
Antibody
100 μg

$363.83

DATA SHEET

Monoclonal Antibody targeting BID for WB.

TargetBID
Product TypeAntibody
ApplicationWB
ClonalityMonoclonal
ConjugateUnlabeled
IsotypeIgG1
ImmunogenRecombinant human Bid (61-118 a.a. end N)
Host SpeciesMouse
Species ReactivityHuman
Formulation100 μg IgG in 100 μl volume of PBS containing 50% glycerol, pH 7.2. No preservative iscontained.
Research AreaApoptosis
Description/Background

Apoptosis is a major form of cell death characterized by several morphological features that include chromatin condensation and fragmentation, cell membrane blebbing, and formation of apoptotic bodies. BID is an apoptosis promoting protein, which possesses
only BH3 domain that is a common structure of Bcl-2 family members. Once full length BID (p22) is cleaved with caspases, cleaved BID (p15) induces a conformational
change and oligomerization of a protein named BAK on mitochondrial membrane. It is thought that oligomerized BAK contribute to forming pores that release cytochrome c
into cytosol.

Storage Temperature-20°C
ProtocolsWB
Clone Number5C9
Concentration1 mg/mL
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
M072-3
Antibody
100 μg

$363.83

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