Anti-Hsp40 (Human) mAb (Monoclonal Antibody)
Monoclonal Antibody targeting HSP40 for IPP, WB.
| Target | HSP40 |
|---|---|
| Product Type | Antibody |
| Application | IP, WB |
| Clonality | Monoclonal |
| Conjugate | Unlabeled |
| Isotype | IgG2a |
| Immunogen | Human full-length Hsp40 (1-340 a.a.) |
| Host Species | Mouse |
| Species Reactivity | Human, Mouse, Rat |
| Formulation | 100 μg IgG in 100 μl volume of PBS containing 50% glycerol, pH 7.2. No preservative iscontained. |
| Research Area | Immunology |
| Description/Background | 40 kDa heat shock protein (Hsp40) is a novel heat shock protein induced by heat shock and other stresses in mammalian and avian cells. The cDNA sequence of the Hsp40 is identical with HDJ1. Deduced amino acid sequence of the Hsp40 cDNA is homologues to DnaJ, an E. coli heat shock protein and its homologues in yeast such as SCJ1, YDJ1 (MAS5), SIS1, SEC63 and zuotin. E. coli’s DnaJ heat shock protein is known to function together with DnaK (Hsp70) and GrpE as a molecular chaperone, which is necessary for assembly and disassembly of protein complexes, protein folding, renaturation of denatured proteins, prevention of protein aggregation and protein export. The Hsp40 is colocalized with Hsp70 in the nuclei and nucleoli of heat-shocked HeLa cells which suggests that Hsp70 (DnaK)-Hsp40 (DnaJ) chaperone system is ubiquitous. |
| Storage Temperature | 4°C |
| Protocols | IP, WB |
| Clone Number | 2.00E+01 |
| Concentration | 1 mg/mL |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |
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