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Anti-Hsp40 (Human) mAb (Monoclonal Antibody)

M039-3
Antibody
100 μg/100 μL

$337.73

DATA SHEET

Monoclonal Antibody targeting HSP40 for IPP, WB.

TargetHSP40
Product TypeAntibody
ApplicationIP, WB
ClonalityMonoclonal
ConjugateUnlabeled
IsotypeIgG2a
ImmunogenHuman full-length Hsp40 (1-340 a.a.)
Host SpeciesMouse
Species ReactivityHuman, Mouse, Rat
Formulation100 μg IgG in 100 μl volume of PBS containing 50% glycerol, pH 7.2. No preservative iscontained.
Research AreaImmunology
Description/Background

40 kDa heat shock protein (Hsp40) is a novel heat shock protein induced by heat shock and other stresses in mammalian and avian cells. The cDNA sequence of the Hsp40 is identical with HDJ1. Deduced amino acid sequence of the Hsp40 cDNA is homologues to DnaJ, an E. coli heat shock protein and its homologues in yeast such as SCJ1, YDJ1 (MAS5), SIS1, SEC63 and zuotin. E. coli’s DnaJ heat shock protein is known to function together with DnaK (Hsp70) and GrpE as a molecular chaperone, which is necessary for assembly and disassembly of protein complexes, protein folding, renaturation of denatured proteins, prevention of protein aggregation and protein export. The Hsp40 is colocalized with Hsp70 in the nuclei and nucleoli of heat-shocked HeLa cells which suggests that Hsp70 (DnaK)-Hsp40 (DnaJ) chaperone system is ubiquitous.

Storage Temperature4°C
ProtocolsIP, WB
Clone Number2.00E+01
Concentration1 mg/mL
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
M039-3
Antibody
100 μg/100 μL

$337.73

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