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Anti-CD40 (Human) mAb Functional Grade (Monoclonal Antibody)

This product is only available in the US
FP10052505
Antibody
50 µg

$201.00

DATA SHEET

The 5C3 monoclonal antibody specifically reacts with human CD40, a 48kDA type I glycoprotein. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The 5C3 antibody partially blocks the binding of CD40L (CD154). In the presence of IL-4 or PMA, the 5C3 antibody promotes B cell proliferation.

Application Notes:
The antibody has been analyzed for quality through the flow cytometric analysis of the relevant cell type. It is recommended that the reagent be titrated for optimal performance for each application.

TargetCD40
Product TypeAntibody
ApplicationFCM, FA
ClonalityMonoclonal
IsotypeIgG1 ĸ
Host SpeciesMouse
Species ReactivityHuman
FormulationPhosphate-buffered aqueous solution, ph7.2.
Research AreaImmunology, Adaptive Immunity, Flow Cytometry
Storage TemperatureThe product should be stored undiluted at 4°C. Do not freeze.
ProtocolsFCM, FA
Clone Number5C3
PurificationThe monoclonal antibody was purified utilizing affinity chromatography
Endotoxin levelsThe endotoxin level is determined by LAL test to be less than 0.01 EU/µg of the protein.
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
This product is only available in the US
FP10052505
Antibody
50 µg

$201.00

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