Anti-CD4 (Mouse) mAb-FITC (Monoclonal Antibody)
Monoclonal antibody conjugating to FITC of 100 tests targeting CD4 for FCM
| Target | CD4 |
|---|---|
| Product Type | Antibody |
| Application | FCM |
| Clonality | Monoclonal |
| Conjugate | FITC |
| Isotype | IgG2b ĸ |
| Immunogen | Cloned cytotoxic T lymphocyte lines V4 and 243/2.5 |
| Host Species | Rat |
| Species Reactivity | Mouse |
| Formulation | 100 tests in 1 mL volume of PBS containing 1% BSA and 0.09% NaN3. *Azide may react with copper or lead in plumbing system to form explosive metal azides. Therefore, always flush plenty of water when disposing materials containing azide into drain. |
| Research Area | Cancer, Immunology |
| Description/Background | The CD4 antigen is a cell surface glycoprotein that is expressed on subsets of thymocytes and mature T lymphocytes, as well as on monocytes and macrophages. CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction and plays an important role in T-helper cell development and activation. This monoclonal antibody GK1.5 reacts with a non-polymorphic epitope on the mouse CD4 and a useful tool for in vivo depletion of CD4+ T cells. |
| Storage Temperature | This antibody solution is stable for one year from the date of purchase when stored at 4°C. |
| Protocols | FCM |
| Clone Number | GK1.5 |
| Source | This antibody was purified from mouse ascites fluid. This hybridoma (clone GK1.5) was established by fusion of mouse myeloma cell SP2/0-Ag14 with Lewis rat splenocyte immunized with the cloned cytotoxic T lymphocyte lines V4 and 243/2.5. |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |
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