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Phospho-E-Cadherin-S838/S840 Rabbit pAb

CNAP1074T
Antibody
100 µl

THIS ITEM HAS BEEN DISCONTINUED

DATA SHEET

TargetCDH1
Product TypeAntibody
ApplicationWB
ClonalityMonoclonal
IsotypeIgG
ImmunogenA synthetic phosphorylated peptide around S838 & S840 of human CDH1 (NP_004351.1).
Host SpeciesRabbit
Species ReactivityHuman
FormulationPBS with 0.01% thimerosal,50% glycerol
Research AreaCancer, Immunology, Epigenetics
Description/Background

Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

ProtocolsWB
Molecular Weight97kDa
PurityAffinity purification
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
CNAP1074T
Antibody
100 µl

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