Phospho-E-Cadherin-S838/S840 Rabbit pAb
Target | CDH1 |
---|---|
Product Type | Antibody |
Application | WB |
Clonality | Monoclonal |
Isotype | IgG |
Immunogen | A synthetic phosphorylated peptide around S838 & S840 of human CDH1 (NP_004351.1). |
Host Species | Rabbit |
Species Reactivity | Human |
Formulation | PBS with 0.01% thimerosal,50% glycerol |
Research Area | Cancer, Immunology, Epigenetics |
Description/Background | Receptor tyrosine kinases play a key role in the communication of cells with their microenvironment. These kinases are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain, and that are activated by various types of collagen. Expression of this protein is restricted to epithelial cells, particularly in the kidney, lung, gastrointestinal tract, and brain. In addition, it has been shown to be significantly overexpressed in several human tumors. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Protocols | WB |
Molecular Weight | 97kDa |
Purity | Affinity purification |
Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |