Phospho-LCK-Y394 Rabbit pAb
Target | Phospho-LCK-Y394 |
---|---|
Product Type | Antibody |
Application | WB |
Clonality | Polyclonal |
Conjugate | unconjugated |
Isotype | IgG |
Immunogen | A synthetic phosphorylated peptide around Y394 of human LCK (NP_005347.3). |
Host Species | Rabbit |
Species Reactivity | Human, Mouse |
Formulation | PBS with 0.05% Proclin300,50% glycerol |
Research Area | Cancer |
Description/Background | The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus. |
Storage Temperature | Store at -20℃ |
Protocols | WB |
Molecular Weight | 58kDa |
Purification | Affinity purification |
Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |