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CD30 Rabbit mAb

CNA9789S
Antibody
100 µl

THIS ITEM HAS BEEN DISCONTINUED

DATA SHEET

TargetTNFRSF8
Product TypeAntibody
ApplicationICC, IF, WB
ClonalityMonoclonal
IsotypeIgG
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 496-595 of human CD30 (P28908).
Host SpeciesRabbit
Species ReactivityHuman, Rat
FormulationPBS with 0.02% sodium azide,0.05% BSA,50% glycerol
Research AreaCancer, Immunology
Description/Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

ProtocolsICC, IF, WB
Molecular Weight64kDa
PurityAffinity purification
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
CNA9789S
Antibody
100 µl

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