PCCA Rabbit pAb
Target | PCCA |
---|---|
Product Type | Antibody |
Application | WB |
Clonality | Polyclonal |
Conjugate | unconjugated |
Isotype | IgG |
Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 449-728 of human PCCA (NP_000273.2). |
Host Species | Rabbit |
Species Reactivity | Mouse, Rat |
Formulation | PBS with 0.05% Proclin300,50% glycerol |
Research Area | Cancer, Metabolism |
Description/Background | The protein encoded by this gene is the alpha subunit of the heterodimeric mitochondrial enzyme Propionyl-CoA carboxylase. PCCA encodes the biotin-binding region of this enzyme. Mutations in either PCCA or PCCB (encoding the beta subunit) lead to an enzyme deficiency resulting in propionic acidemia. Multiple transcript variants encoding different isoforms have been found for this gene. |
Storage Temperature | Store at -20℃ |
Protocols | WB |
Molecular Weight | 80kDa |
Purification | Affinity purification |
Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |