FBXW11 Rabbit pAb
Target | FBXW11 |
---|---|
Product Type | Antibody |
Application | IF/ICC, WB |
Clonality | Polyclonal |
Conjugate | unconjugated |
Isotype | IgG |
Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-85 of human FBXW11 (NP_036432.2). |
Host Species | Rabbit |
Species Reactivity | Human |
Formulation | PBS with 0.09% Sodium azide,50% glycerol |
Research Area | Cancer |
Description/Background | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. |
Storage Temperature | Store at -20℃ |
Protocols | IF/ICC, WB |
Molecular Weight | 62kDa |
Purification | Affinity purification |
Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |