Coagulation Protein C Rabbit mAb
| Target | PROC |
|---|---|
| Product Type | Antibody |
| Application | ICC, IF, WB |
| Clonality | Monoclonal |
| Isotype | IgG |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 300-461 of human Coagulation Coagulation Protein C (P04070). |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse, Rat |
| Formulation | PBS with 0.02% sodium azide,0.05% BSA,50% glycerol |
| Research Area | Cancer, Immunology |
| Description/Background | This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis. |
| Protocols | ICC, IF, WB |
| Molecular Weight | 52kDa |
| Purity | Affinity purification |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |