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GRIN2B Rabbit pAb

CNA3056S1
100 µl

THIS ITEM HAS BEEN DISCONTINUED

DATA SHEET

TargetRecombinant fusion protein containing a sequence corresponding to amino acids 1185-1484 of human GRIN2B (NP_000825.2).
Product TypeAntibody
ApplicationIF/ICC, WB
ClonalityPolyclonal
Conjugateunconjugated
IsotypeIgG
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1185-1484 of human GRIN2B (NP_000825.2).
Host SpeciesRabbit
Species ReactivityHuman, Mouse, Rat
FormulationPBS with 0.09% Sodium azide,50% glycerol
Research AreaCancer
Description/BackgroundThis gene encodes a member of the N-methyl-D-aspartate (NMDA) receptor family within the ionotropic glutamate receptor superfamily. The encoded protein is a subunit of the NMDA receptor ion channel which acts as an agonist binding site for glutamate. The NMDA receptors mediate a slow calcium-permeable component of excitatory synaptic transmission in the central nervous system. The NMDA receptors are heterotetramers of seven genetically encoded, differentially expressed subunits including NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The early expression of this gene in development suggests a role in brain development, circuit formation, synaptic plasticity, and cellular migration and differentiation. Naturally occurring mutations within this gene are associated with neurodevelopmental disorders including autism spectrum disorder, attention deficit hyperactivity disorder, epilepsy, and schizophrenia.
Storage TemperatureStore at -20℃
ProtocolsIF/ICC, WB
Molecular Weight166kDa
PurificationAffinity purification
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
CNA3056S1
100 µl

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