EDA Rabbit pAb
| Target | EDA |
|---|---|
| Product Type | Antibody |
| Application | IF/ICC, IHC (P), WB |
| Clonality | Polyclonal |
| Conjugate | unconjugated |
| Isotype | IgG |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 750-850 of human EDA (Q92838). |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse, Rat |
| Formulation | PBS with 0.05% Proclin300,50% glycerol |
| Research Area | Cancer |
| Description/Background | The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein, which belongs to the tumor necrosis factor family, acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia, anhidrotic, which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene. |
| Storage Temperature | Store at -20℃ |
| Protocols | IF/ICC, IHC (P), WB |
| Molecular Weight | 41kDa |
| Purification | Affinity purification |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |