Granzyme B Rabbit pAb
| Target | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Granzyme B (NP_004122.2). |
|---|---|
| Product Type | Antibody |
| Application | IF/ICC, IHC (P), WB |
| Clonality | Polyclonal |
| Conjugate | unconjugated |
| Isotype | IgG |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human Granzyme B (NP_004122.2). |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse, Rat |
| Formulation | PBS with 0.09% Sodium azide,50% glycerol |
| Research Area | Cancer |
| Description/Background | This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This Protein A Affinity purificationlso processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis. |
| Storage Temperature | Store at -20℃ |
| Protocols | IF/ICC, IHC (P), WB |
| Molecular Weight | 28kDa |
| Purification | Affinity purification |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |