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Integrin alpha V (ITGAV/CD51) Rabbit pAb

CNA2091S1
100 µl

THIS ITEM HAS BEEN DISCONTINUED

DATA SHEET

TargetIntegrin alpha V (ITGAV/CD51)
Product TypeAntibody
ApplicationIHC (P), IP, WB
ClonalityPolyclonal
Conjugateunconjugated
IsotypeIgG
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 950 to the C-terminus of human Integrin alpha V (ITGAV/CD51) (NP_002201.1).
Host SpeciesRabbit
Species ReactivityHuman, Mouse, Rat
FormulationPBS with 0.09% Sodium azide,50% glycerol
Research AreaCancer
Description/BackgroundThe product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit. This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits. The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor. This integrin may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.
Storage TemperatureStore at -20℃
ProtocolsIHC (P), IP, WB
Molecular Weight116kDa
PurificationAffinity purification
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
CNA2091S1
100 µl

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