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TriMethyl-Histone H3-K36 Rabbit mAb

CNA20379P
Antibody
100 µl

THIS ITEM HAS BEEN DISCONTINUED

DATA SHEET

TargetHistone H3
Product TypeAntibody
ApplicationChIP, ChIP-seq, IHC (P), IP, WB
ClonalityMonoclonal
IsotypeIgG
ImmunogenA synthetic trimethylated peptide around K36 of human Histone H3 (NP_003520.1).
Host SpeciesRabbit
Species ReactivityHuman, Mouse, Other (Wide Range), Rat
FormulationPBS with 0.05% proclin300,0.05% BSA,50% glycerol
Research AreaCancer, Immunology, Epigenetics
Description/Background

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

ProtocolsChIP, ChIP-seq, IHC (P), IP, WB
Molecular Weight15kDa
Concentration1 mg/mL
PurityAffinity purification
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
CNA20379P
Antibody
100 µl

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