Acetyl-Histone H4-K16 Rabbit pAb
Target | H4C14 |
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Product Type | Antibody |
Application | WB |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | A synthetic acetylated peptide around K16 of human Histone H4 (NP_003539.1). |
Host Species | Rabbit |
Species Reactivity | Human, Mouse, Other (Wide Range), Rat |
Formulation | PBS with 0.01% thimerosal,50% glycerol |
Research Area | Cancer, Immunology |
Description/Background | Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H4 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy. |
Protocols | WB |
Molecular Weight | 11kDa |
Purity | Affinity purification |
Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |