KRAS+HRAS+NRAS Rabbit mAb
Target | HRAS/KRAS/KRAS |
---|---|
Product Type | Antibody |
Application | ICC, IF, WB |
Clonality | Monoclonal |
Isotype | IgG |
Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-188 of human NRAS (P01111). |
Host Species | Rabbit |
Species Reactivity | Human, Mouse, Rat |
Formulation | PBS with 0.02% sodium azide,0.05% BSA,50% glycerol |
Research Area | Cancer |
Description/Background | This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008] |
Protocols | ICC, IF, WB |
Molecular Weight | 21kDa |
Purity | Affinity purification |
Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |