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CD44 Rabbit mAb

CNA19020P
Antibody
100 µl

THIS ITEM HAS BEEN DISCONTINUED

DATA SHEET

TargetCD44
Product TypeAntibody
ApplicationFCM, ICC, IF, IHC (P), WB
ClonalityMonoclonal
IsotypeIgG
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 20-178 of human CD44 (NP_000601.3).
Host SpeciesRabbit
Species ReactivityHuman
FormulationPBS with 0.05% proclin300,0.05% BSA,50% glycerol
Research AreaCancer, Immunology
Description/Background

The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

ProtocolsFCM, ICC, IF, IHC (P), WB
Molecular Weight82kDa
PurityAffinity purification
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
CNA19020P
Antibody
100 µl

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