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Alpha-Fetoprotein (AFP) Mouse mAb

CNA17898T
Antibody
100 µl

THIS ITEM HAS BEEN DISCONTINUED

DATA SHEET

TargetAFP
Product TypeAntibody
ApplicationICC, IF, IHC (P), WB
ClonalityMonoclonal
IsotypeIgG1kappa
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 19-609 of human Alpha-Fetoprotein (AFP).
Host SpeciesMouse
Species ReactivityHuman, Mouse, Rat
FormulationPBS with 0.01% thimerosal,50% glycerol
Research AreaCancer, Immunology
Description/Background

This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoProtein A Affinity purificationnd albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

ProtocolsICC, IF, IHC (P), WB
Molecular Weight69kDa
PurityAffinity purification
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
CNA17898T
Antibody
100 µl

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