NFATC4 Rabbit pAb
| Target | NFATC4 |
|---|---|
| Product Type | Antibody |
| Application | WB |
| Clonality | Polyclonal |
| Isotype | IgG |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 560-710 of human NFATC4 (NP_004545.2). |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse |
| Formulation | PBS with 0.01% thimerosal,50% glycerol |
| Research Area | Cancer, Immunology, Epigenetics |
| Description/Background | This gene encodes a member of the nuclear factor of activated T cells (NFAT) protein family. The encoded protein is part of a DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor stimulation and an inducible nuclear component. NFAT proteins are activated by the calmodulin-dependent phosphatase, calcineurin. The encoded protein plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of interleukin-2 and interleukin-4. Alternative splicing results in multiple transcript variants. |
| Protocols | WB |
| Molecular Weight | 95kDa |
| Purity | Affinity purification |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |