FXN / Frataxin Rabbit pAb
Target | FXN |
---|---|
Product Type | Antibody |
Application | IF/ICC, IHC (P), WB |
Clonality | Polyclonal |
Conjugate | unconjugated |
Isotype | IgG |
Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 42-210 of human FXN / Frataxin (NP_000135.2). |
Host Species | Rabbit |
Species Reactivity | Human, Mouse, Rat |
Formulation | PBS with 0.05% Proclin300,50% glycerol |
Research Area | Cancer, Metabolism |
Description/Background | This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants. |
Storage Temperature | Store at -20℃ |
Protocols | IF/ICC, IHC (P), WB |
Molecular Weight | 23kDa |
Purification | Affinity purification |
Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |