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CD11a/LFA-1A/ITGAL Rabbit pAb

CNA16903T
Antibody
100 µl

THIS ITEM HAS BEEN DISCONTINUED

DATA SHEET

TargetITGAL
Product TypeAntibody
ApplicationWB
ClonalityPolyclonal
IsotypeIgG
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-1170 of human CD11a/LFA-1A/CD11a/LFA-1A/ITGAL (P20701).
Host SpeciesRabbit
Species ReactivityHuman, Rat
FormulationPBS with 0.01% thimerosal,50% glycerol
Research AreaCancer, Immunology
Description/Background

ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.

ProtocolsWB
Molecular Weight129kDa
PurityAffinity purification
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
CNA16903T
Antibody
100 µl

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