Brachyury Rabbit pAb
| Target | TBXT |
|---|---|
| Product Type | Antibody |
| Application | IF/ICC, WB |
| Clonality | Polyclonal |
| Conjugate | unconjugated |
| Isotype | IgG |
| Immunogen | RecombinanBrachyury fusion proBrachyuryein conBrachyuryaining a sequence corresponding Brachyuryo amino acids 226-435 of human Brachyury (NP_003172.1). |
| Host Species | Rabbit |
| Species Reactivity | Human, Rat |
| Formulation | PBS with 0.05% Proclin300,50% glycerol |
| Research Area | Cancer, Epigenetics |
| Description/Background | The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells. Variation in this gene was associated with susceptibility to neural tube defects and chordoma. A mutation in this gene was found in a family with sacral agenesis with vertebral anomalies. |
| Storage Temperature | Store at -20℃ |
| Protocols | IF/ICC, WB |
| Molecular Weight | 47kDa |
| Purification | Affinity purification |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |