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Glucosylceramidase beta (GBA) Rabbit pAb

CNA16860S
Antibody
100 µl

THIS ITEM HAS BEEN DISCONTINUED

DATA SHEET

TargetGBA1
Product TypeAntibody
ApplicationWB
ClonalityPolyclonal
IsotypeIgG
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 40-250 of human Glucosylceramidase beta (Glucosylceramidase beta (GBA)) (NP_000148.2).
Host SpeciesRabbit
Species ReactivityHuman, Rat
FormulationPBS with 0.02% sodium azide,50% glycerol
Research AreaCancer, Immunology, Metabolism
Description/Background

This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.

ProtocolsWB
Molecular Weight60kDa
PurityAffinity purification
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
CNA16860S
Antibody
100 µl

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