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COPA Rabbit pAb

CNA16821T
Antibody
100 µl

THIS ITEM HAS BEEN DISCONTINUED

DATA SHEET

TargetCOPA
Product TypeAntibody
ApplicationWB
ClonalityPolyclonal
IsotypeIgG
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 550-650 of human COPA (NP_001091868.1).
Host SpeciesRabbit
Species ReactivityMouse
FormulationPBS with 0.01% thimerosal,50% glycerol
Research AreaCancer, Immunology
Description/Background

In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms.

ProtocolsWB
Molecular Weight138kDa
PurityAffinity purification
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
CNA16821T
Antibody
100 µl

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