CACNA1D Rabbit pAb
Target | CACNA1D |
---|---|
Product Type | Antibody |
Application | WB |
Clonality | Polyclonal |
Isotype | IgG |
Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1882-2181 of human CACNA1D (NP_000711.1). |
Host Species | Rabbit |
Species Reactivity | Human, Rat |
Formulation | PBS with 0.01% thimerosal,50% glycerol |
Research Area | Cancer, Immunology, Metabolism |
Description/Background | Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene. |
Protocols | WB |
Molecular Weight | 245kDa |
Purity | Affinity purification |
Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |