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Fibrillin 1 Rabbit pAb

CNA16677P
100 µl

THIS ITEM HAS BEEN DISCONTINUED

DATA SHEET

TargetFBN1
Product TypeAntibody
ApplicationIF/ICC, IHC (P), WB
ClonalityPolyclonal
Conjugateunconjugated
IsotypeIgG
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 360-460 of human Fibrillin 1 (NP_000129.3).
Host SpeciesRabbit
Species ReactivityHuman, Mouse, Rat
FormulationPBS with 0.05% Proclin300,50% glycerol
Research AreaCancer
Description/BackgroundThis gene encodes a member of the fibrillin family of proteins. The encoded preproprotein is proteolytically processed to generate two proteins including the extracellular matrix component fibrillin-1 and the protein hormone asprosin. Fibrillin-1 is an extracellular matrix glycoprotein that serves as a structural component of calcium-binding microfibrils. These microfibrils provide force-bearing structural support in elastic and nonelastic connective tissue throughout the body. Asprosin, secreted by white adipose tissue, has been shown to regulate glucose homeostasis. Mutations in this gene are associated with Marfan syndrome and the related MASS phenotype, as well as ectopia lentis syndrome, Weill-Marchesani syndrome, Shprintzen-Goldberg syndrome and neonatal progeroid syndrome.
Storage TemperatureStore at -20℃
ProtocolsIF/ICC, IHC (P), WB
Molecular Weight312kDa
PurificationAffinity purification
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
CNA16677P
100 µl

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