PCM1 Rabbit pAb
Target | PCM1 |
---|---|
Product Type | Antibody |
Application | IF/ICC, WB |
Clonality | Polyclonal |
Conjugate | unconjugated |
Isotype | IgG |
Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PCM1 (NP_006188.4). |
Host Species | Rabbit |
Species Reactivity | Human |
Formulation | PBS with 0.05% Proclin300,50% glycerol |
Research Area | Cancer, Epigenetics |
Description/Background | The protein encoded by this gene is a component of centriolar satellites, which are electron dense granules scattered around centrosomes. Inhibition studies show that this protein is essential for the correct localization of several centrosomal proteins, and for anchoring microtubules to the centrosome. Chromosomal aberrations involving this gene are associated with papillary thyroid carcinomas and a variety of hematological malignancies, including atypical chronic myeloid leukemia and T-cell lymphoma. Multiple transcript variants encoding different isoforms have been found for this gene. |
Storage Temperature | Store at -20℃ |
Protocols | IF/ICC, WB |
Molecular Weight | 229kDa |
Purification | Affinity purification |
Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |