NLRP6 Rabbit pAb
| Target | NLRP6 |
|---|---|
| Product Type | Antibody |
| Application | WB |
| Clonality | Polyclonal |
| Conjugate | unconjugated |
| Isotype | IgG |
| Immunogen | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human NLRP6 (NP_001263629.1). |
| Host Species | Rabbit |
| Species Reactivity | Human, Mouse, Rat |
| Formulation | PBS with 0.05% proclin300,50% glycerol |
| Research Area | Cancer, Immunology |
| Description/Background | The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded Protein A Affinity purificationlso mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene. |
| Protocols | WB |
| Molecular Weight | 99kDa |
| Purity | Affinity purification |
| Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |