SMPD4 Rabbit pAb
Target | SMPD4 |
---|---|
Product Type | Antibody |
Application | ICC, IF, WB |
Clonality | Polyclonal |
Conjugate | unconjugated |
Isotype | IgG |
Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 600-800 of human SMPD4 (NP_060421.2). |
Host Species | Rabbit |
Species Reactivity | Human, Mouse |
Formulation | PBS with 0.01% thimerosal,50% glycerol |
Research Area | Cancer, Immunology |
Description/Background | The protein encoded by this gene is a sphingomyelinase that catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. This gene is activated by DNA damage, cellular stress, and tumor necrosis factor, but it is downregulated by wild-type p53. The encoded protein localizes to the endoplasmic reticulum and Golgi network. |
Protocols | ICC, IF, WB |
Molecular Weight | 98kDa |
Purity | Affinity purification |
Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |