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SEMA3C Rabbit pAb

CNA15386P
100 µl

THIS ITEM HAS BEEN DISCONTINUED

DATA SHEET

TargetSEMA3C
Product TypeAntibody
ApplicationIF/ICC, WB
ClonalityPolyclonal
Conjugateunconjugated
IsotypeIgG
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 21-330 of human SEMA3C (NP_006370.1).
Host SpeciesRabbit
Species ReactivityHuman, Mouse
FormulationPBS with 0.05% Proclin300,50% glycerol
Research AreaCancer
Description/BackgroundThis gene encodes a secreted glycoprotein that belongs to the semaphorin class 3 family of neuronal guidance cues. The encoded protein contains an N-terminal sema domain, integrin and immunoglobulin-like domains, and a C-terminal basic domain. Homodimerization and proteolytic cleavage of the C-terminal propeptide are necessary for the function of the encoded protein. It binds a neuropilin co-receptor before forming a heterotrimeric complex with an associated plexin. An increase in the expression of this gene correlates with an increase in cancer cell invasion and adhesion. Naturally occurring mutations in this gene are associated with Hirschsprung disease.
Storage TemperatureStore at -20℃
ProtocolsIF/ICC, WB
Molecular Weight85kDa
PurificationAffinity purification
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
CNA15386P
100 µl

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