Fukutin Rabbit mAb
Target | FKTN |
---|---|
Product Type | Antibody |
Application | IHC (P), WB |
Clonality | Monoclonal |
Conjugate | unconjugated |
Isotype | IgG |
Immunogen | A synthetic peptide corresponding to a sequence within amino acids 362-461 of human Fukutin (O75072). |
Host Species | Rabbit |
Species Reactivity | Human, Mouse, Rat |
Formulation | PBS with 0.02% sodium azide,0.05% BSA,50% glycerol |
Research Area | Cancer, Immunology |
Description/Background | The protein encoded by this gene is a putative transmembrane protein that is localized to the cis-Golgi compartment, where it may be involved in the glycosylation of alpha-dystroglycan in skeletal muscle. The encoded protein is thought to be a glycosyltransferase and could play a role in brain development. Defects in this gene are a cause of Fukuyama-type congenital muscular dystrophy (FCMD), Walker-Warburg syndrome (WWS), limb-girdle muscular dystrophy type 2M (LGMD2M), and dilated cardiomyopathy type 1X (CMD1X). Alternatively spliced transcript variants have been found for this gene. |
Protocols | IHC (P), WB |
Molecular Weight | 54kDa |
Purity | Affinity purification |
Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |