CD138/Syndecan-1 Rabbit pAb
Target | SDC1 |
---|---|
Product Type | Antibody |
Application | IHC (P), WB |
Clonality | Polyclonal |
Conjugate | unconjugated |
Isotype | IgG |
Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 25-240 of human CD138/Syndecan-1 (NP_002988.4). |
Host Species | Rabbit |
Species Reactivity | Human, Mouse |
Formulation | PBS with 0.05% proclin300,50% glycerol |
Research Area | Cancer, Immunology, Metabolism |
Description/Background | The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane Protein A Affinity purificationnd participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. |
Protocols | IHC (P), WB |
Molecular Weight | 32kDa |
Purity | Affinity purification |
Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |