VDAC3 Rabbit pAb
Target | VDAC3 |
---|---|
Product Type | Antibody |
Application | ICC, IF, IHC (P), WB |
Clonality | Polyclonal |
Conjugate | unconjugated |
Isotype | IgG |
Immunogen | A synthetic peptide corresponding to a sequence within amino acids 100-200 of human VDAC3 (NP_005653.3). |
Host Species | Rabbit |
Species Reactivity | Human, Mouse |
Formulation | PBS with 0.05% proclin300,50% glycerol |
Research Area | Cancer, Immunology, Metabolism |
Description/Background | This gene encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation of adenine nucleotides, and are hypothesized to form part of the mitochondrial permeability transition pore, which results in the release of cytochrome c at the onset of apoptotic cell death. Alternatively transcript variants encoding different isoforms have been described for this gene. |
Protocols | ICC, IF, IHC (P), WB |
Molecular Weight | 31kDa |
Purity | Affinity purification |
Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |