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OTUB1 Rabbit pAb

CNA10313S
Antibody
100 µl

THIS ITEM HAS BEEN DISCONTINUED

DATA SHEET

TargetOTUB1
Product TypeAntibody
ApplicationWB
ClonalityPolyclonal
Conjugateunconjugated
IsotypeIgG
ImmunogenA synthetic peptide corresponding to a sequence within amino acids 50-150 of human OTUB1 (NP_060140.2).
Host SpeciesRabbit
Species ReactivityHuman, Mouse
FormulationPBS with 0.02% sodium azide,50% glycerol
Research AreaCancer, Immunology, Epigenetics
Description/Background

The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants.

ProtocolsWB
Molecular Weight31kDa
PurityAffinity purification
Regulatory StatementFor Research Use Only. Not for use in diagnostic procedures.
CNA10313S
Antibody
100 µl

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