α-Smooth Muscle Actin (ACTA2) Rabbit pAb
Target | ACTA2 |
---|---|
Product Type | Antibody |
Application | ICC, IF, WB |
Clonality | Polyclonal |
Conjugate | unconjugated |
Isotype | IgG |
Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 1-124 of human α-Smooth Muscle Actin (ACTA2) (NP_001135417.1). |
Host Species | Rabbit |
Species Reactivity | Human, Mouse, Rat |
Formulation | PBS with 0.05% proclin300,50% glycerol |
Research Area | Cancer, Immunology |
Description/Background | This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a smooth muscle actin that is involved in vascular contractility and blood pressure homeostasis. Mutations in this gene cause a variety of vascular diseases, such as thoracic aortic disease, coronary artery disease, stroke, and Moyamoya disease, as well as multisystemic smooth muscle dysfunction syndrome. |
Protocols | ICC, IF, WB |
Molecular Weight | 42kDa |
Purity | Affinity purification |
Regulatory Statement | For Research Use Only. Not for use in diagnostic procedures. |